TY  - JOUR
AU  - Sánchez Sánchez, Roberto
AU  - Huertas López, Ana
AU  - Largo de la Torre, Andrea
AU  - Ferré Pérez, Ignacio
AU  - Dini, Filippo Maria
AU  - Re, Michela Tatiana
AU  - Moreno Gonzalo, Javier
AU  - Chol, Ryan
AU  - Hulverson, Matthew A.
AU  - Ojo, Kayode K.
AU  - Arnold, Samuel L. M.
AU  - Hemphill, Andrew
AU  - Van Voorhis, Wesley C.
AU  - Ortega Mora, Luis Miguel
PY  - 2025
DO  - 10.1128/aac.01448-24
SN  - 0066-4804
UR  - https://hdl.handle.net/20.500.14352/118451
T2  - Antimicrobial Agents and Chemotherapy
AB  - Drug development for congenital toxoplasmosis is challenging since first-line therapy has a high rate of adverse effects and exhibits suboptimal efficacy. Bumped kinase inhibitors (BKIs), targeting protein kinases with small gatekeeper residues, have...
LA  - eng
M2  - 1
PB  - ASM Journals
KW  - Toxoplasma gondii
KW  - Sheep
KW  - Congenital toxoplasmosis
KW  - BKI-1748
KW  - Treatment
TI  - Treatment with BKI-1748 after Toxoplasma gondii systemic dissemination in experimentally infected pregnant sheep improves fetal and lamb mortality and morbidity and prevents congenital infection
TY  - journal article
VL  - 69
ER  -