TY  - JOUR
AU  - Marrero-Hernández, Sara
AU  - Márquez-Arce, Daniel
AU  - Cabrera-Rodríguez, Romina
AU  - Estévez-Herrera, Judith
AU  - Pérez-Yanes, Silvia
AU  - Barroso-González, Jonathan
AU  - Madrid, Ricardo
AU  - Machado, José David
AU  - Blanco, Julia
AU  - Valenzuela-Fernández, Agustín
PY  - 2019
DO  - 10.3389/fmicb.2019.02437
SN  - 1664-302X
UR  - https://hdl.handle.net/20.500.14352/6379
T2  - Frontiers in Microbiology
AB  - HIV Nef is a central auxiliary protein in HIV infection and pathogenesis. Our results indicate that HDAC6 promotes the aggresome/autophagic degradation of the viral polyprotein Pr55Gag to inhibit HIV-1 production. Nef counteracts this antiviral...
AB  - Julià Blanco5,6 and Agustín Valenzuela-Fernández1
LA  - eng
M2  - 1
PB  - Frontiers Media
KW  - HIV-1
KW  - Nef
KW  - HDAC6
KW  - Pr55Gag
KW  - acidic-endocytic/lysosomal degradation
KW  - autophagy
KW  - infection
KW  - viralproduction
TI  - HIV-1 Nef Targets HDAC6 to Assure Viral Production and Virus Infection
TY  - journal article
VL  - 10
ER  -