TY  - JOUR
AU  - Escudero García-Calderón, José Antonio
AU  - Nivina, Aleksandra
AU  - Cambray, Guillaume
AU  - López Igual, Rocío
AU  - Loot, Céline
AU  - Mazel, Didier
PY  - 2017
DO  - 10.1002/bit.26450
SN  - 1097-0290
UR  - https://hdl.handle.net/20.500.14352/19289
T2  - Biotechnology and Bioengineering.
AB  - Synthetic DNA design needs to harness the many information layers embedded in a DNA string. We previously developed the Evolutionary Landscape Painter (ELP), an algorithm that exploits the degeneracy of the code to increase protein evolvability. Here,...
LA  - eng
M2  - 184
PB  - Wiley
KW  - DNA design
KW  - Integrons
KW  - MRNA secondary structure
KW  - Optimized gene
KW  - Synonymous genes
KW  - Synthetic biology
TI  - Recoding of synonymous genes to expand evolutionary landscapes requires control of secondary structure affecting translation
TY  - journal article
VL  - 115
ER  -