RT Journal Article
T1 Chemical characterization and enzyme inhibitory activity of the essential oil of 'etlingera triorgyalis' (baker) R.M.Sm
A1 Fauzi, Sabrina Wafi Mohamad
A1 Salleh, Wan Mohd Nuzul Hakimi Wan
A1 Salihu, Abubakar Siddiq
A1 Rahim, Faezatul Alwani Mohd
A1 Zaini, Nur Nabilah Mohd
A1 Ghani, Nurunajah Ab
A1 Palá Paúl, Jesús
AB This is the first report about the chemical profile and biological properties of the essential oil of Etlingera triorgyalis (Baker) R.M.Sm from their rhizome extracted by hydrodistillation and analysed by GC and GS-MS. A total of 28 constituents, representing 94.1% of the total composition, were identified. The main compounds were neral (48.5%), geranial (10.5%), α-cadinol (7.7%), methyl eugenol (6.5%), and (Z)-isocitral (4.6%). The biological potential of the oil was examined through enzyme-based assays, including acetylcholinesterase inhibition (Ellman method), tyrosinase inhibition (mushroom tyrosinase), and lipoxygenase inhibition. The essential oil showed notable enzyme inhibition, with IC50 values of 133.2 µg/mL (acetylcholinesterase), 118.5 µg/mL (tyrosinase), and 128.4 µg/mL (lipoxygenase). These findings suggest that the essential oil of E. triorgyalis holds promise as a multifunctional natural product with potential applications in managing neurodegenerative disorders, pigmentation issues, and inflammatory conditions.
PB Taylor and Francis
SN 1478-6419
YR 2025
FD 2025-11
LK https://hdl.handle.net/20.500.14352/133410
UL https://hdl.handle.net/20.500.14352/133410
LA eng
NO Fauzi, S. W. M., Salleh, W. M. N. H. W., Salihu, A. S., Rahim, F. A. M., Zaini, N. N. M., Ghani, N. A., & Palá-Paúl, J. (2025). Chemical characterization and enzyme inhibitory activity of the essential oil of etlingera triorgyalis (baker) R.M.Sm. Natural Product Research, 1–6. https://doi.org/10.1080/14786419.2025.2583345
NO Funding:This research was supported by the Geran Penyelidikan Universiti (Kecemerlangan@UPSI) under grant number 2025-0012-103-01, funded by Universiti Pendidikan Sultan Idris.
NO Universiti Pendidikan Sultan Idris
DS Docta Complutense
RD 21 mar 2026