TY  - JOUR
AU  - Vargas Balbuena, Javier
AU  - Otros, ...
PY  - 2022
DO  - 10.1038/s41467-022-29928-8
SN  - 2041-1723
UR  - https://hdl.handle.net/20.500.14352/71574
T2  - Nature communications
AB  - The authors determined high-resolution cryo-EM structures of the lentiviral intasome - the nucleoprotein complex that inserts viral DNA into a host chromosome - and show that the architecture comprising 16 integrase subunits is critical for its...
LA  - eng
PB  - Nature Porfolio
KW  - Immunodeficiency-virus type-1
KW  - Particle cryo-em
KW  - Hiv-1 integrase
KW  - Structural basis
KW  - Crystal-structure
KW  - Retroviral integration
KW  - Nucleotide-sequence
KW  - Ledgf/P75 interacts
KW  - Site selection
KW  - Replication
TI  - Multivalent interactions essential for lentiviral integrase function
TY  - journal article
VL  - 13
ER  -