TY - JOUR AU - Cruz García, Jesús Manuel de la AU - Bamford, Richard N. AU - Burdine, Rebecca D. AU - Roessler, Erich AU - Barkovich, A. James AU - Donnai, Dian AU - Schier, Alexander F. AU - Muenke, Maximiliam PY - 2002 DO - 10.1007/s00439-002-0709-3 SN - 0340-6717 UR - https://hdl.handle.net/20.500.14352/59123 T2 - Human Genetics AB - TDGF1 (CRIPTO) is an EGF-CFC family member and an obligate co-receptor involved in NODAL signaling, a developmental program implicated in midline, forebrain, and left-right axis development in model organisms. Previous studies of CFC1 (CRYPTIC),... LA - eng M2 - 422 PB - Springer-Verlag KW - One-Eyed Pinhead KW - Right Axis Formation KW - Vertebrate Development KW - Zebrafish Organizer KW - Laterality Defects KW - Gene KW - Mouse KW - Gastrulation KW - Cripto KW - Requirement TI - A loss-of-function mutation in the CFC domain of TDGF1 is associated with human forebrain defects TY - journal article VL - 110 ER -