RT Journal Article
T1 Trends in Incidence and Outcomes of Hospitalizations for Urinary Tract Infection among Older People in Spain (2001–2018)
A1 Palacios Ceña, Domingo
A1 Florencio, Lidiane Lima
A1 Hernández  Barrera, Valentín
A1 Fernández de las Peñas, César
A1 Miguel Díez, Javier De
A1 Martínez Hernández, David
A1 Carabantes Alarcón, David
A1 Jiménez García, Rodrigo
A1 López De Andrés, Ana Isabel
A1 López Herranz, Marta
AB (1) Background: To assess time trends in the incidence and in-hospital outcomes of urinary tract infection (UTI) in older people (≥65 years) in Spain (2001–2018) according to sex and to identify the factors independently associated with in-hospital mortality (IHM). (2) Methods: Using the Spanish National Hospital Database, we analyzed comorbidity, procedures, diagnosis, isolated microorganisms, and outcomes. (3) Results: We included 583,693 admissions (56.76% women). In both sexes, the incidence increased with age over time (p < 0.001). In men and women, the highest IHM was found among the oldest patients (>84 years) with values of 9.16% and 8.6%, respectively. The prevalence of bacteremia increased from 4.61% to 4.98% from 2001 to 2018 (p < 0.001) and sepsis decreased from 3.16% to 1.69% (p < 0.001). The risk of dying increased with age (>84 years) (OR 3.63; 95% CI 3.5–3.78) and with almost all comorbidities. Urinary catheter was a risk factor for women (OR 1.1; 95% CI 1.02–1.18) and protective for men (OR 0.71; 95% CI 0.66–0.76). Isolation of Staphylococcus aureus increased the risk of IHM by 40% among men (OR 1.4; 95% CI 1.28–1.53). After adjusting for confounders, IHM decreased over time. (4) Conclusions: The incidence of UTIs was higher in older patients and increased over time; however, IHM decreased during the same period. Female sex, age, comorbidities, sepsis, and a Staphylococcus aureus isolation increased risk of IHM.
PB MPDI
SN 2077-0383
YR 2021
FD 2021-05-26
LK https://hdl.handle.net/20.500.14352/6973
UL https://hdl.handle.net/20.500.14352/6973
LA eng
NO Palacios Ceña, DD., Florencio, L. L., Hernández Barrera, V. et al. «Trends in Incidence and Outcomes of Hospitalizations for Urinary Tract Infection among Older People in Spain (2001–2018)». Journal of Clinical Medicine, vol. 10, n.o 11, mayo de 2021, p. 2332. DOI.org (Crossref), https://doi.org/10.3390/jcm10112332.
DS Docta Complutense
RD 21 abr 2025