TY - JOUR AU - Salloum, Zeina AU - Dauner, Kristin AU - Yun-feng, Li AU - Verma, Neha AU - Valdivieso González, David AU - Almendro Vedia, Víctor G. AU - Almendro Vedia, Víctor Galileo AU - Zhang, John D AU - Nakka, Kiran AU - Xi Chen, Mei AU - McDonald, Jeffrey AU - Corley, Chase D AU - Sorisky, Alexander AU - Song,Bao-Liang AU - López Montero, Iván AU - Luo, Jie AU - Dilworth, Jeffrey F AU - Zha, Xiaohui PY - 2024 DO - 10.7554/eLife.85964 UR - https://hdl.handle.net/20.500.14352/115521 T2 - Elife AB - Statins are known to be anti-inflammatory, but the mechanism remains poorly understood. Here, we show that macrophages, either treated with statin in vitro or from statin-treated mice, have reduced cholesterol levels and higher expression of Jmjd3, a... LA - eng M2 - 1 PB - eLife Sciences Publications, Ltd KW - Cell biology KW - Cholesterol KW - Inflammation KW - Macrophages KW - Mouse TI - Statin-mediated reduction in mitochondrial cholesterol primes an anti-inflammatory response in macrophages by upregulating Jmjd3 TY - journal article VL - 13 ER -