RT Journal Article T1 Diabetes Mellitus and Its Implications in Aortic Stenosis Patients A1 Mouriño Álvarez, Laura A1 Corbacho Alonso, Nerea A1 Sastre Oliva, Tamara A1 Corros Vicente, Cecilia A1 Solis, Jorge A1 Tejerina Sánchez, Teresa A1 Padial, Luis R. A1 Barderas, Maria G. AB Aortic stenosis (AS) and diabetes mellitus (DM) are both progressive diseases that if left untreated, result in significant morbidity and mortality. Several studies revealed that the prevalence of DM is substantially higher in patients with AS and, thus, the progression from mild to severe AS is greater in those patients with DM. DM and common comorbidities associated with both diseases, DM and AS, increase patient management complexity and make aortic valve replacement the only effective treatment. For that reason, a better understanding of the pathogenesis underlying both these diseases and the relationships between them is necessary to design more appropriate preventive and therapeutic approaches. In this review, we provided an overview of the main aspects of the relationship between AS and DM, including common comorbidities and risk factors. We also discuss the established treatments/therapies in patients with AS and DM. PB MPDI SN 1422-0067 YR 2021 FD 2021-06-09 LK https://hdl.handle.net/20.500.14352/7049 UL https://hdl.handle.net/20.500.14352/7049 LA eng NO Instituto de Salud Carlos III (ISCIII)/ FEDER DS Docta Complutense RD 14 may 2024