RT Journal Article
T1 N-(Diazoacetyl)oxazolidin-2-thiones as Sulfur-Donor Reagents: Asymmetric Synthesis of Thiiranes from Aldehydes
A1 Cano Rico, Israel
A1 Gómez-Bengoa, Enrique
A1 Landa, Aitor
A1 Maestro, Miguel
A1 Mielgo, Antonia
A1 Olaizola, Iurre
A1 Oiarbide, Mikel
A1 Palomo, Claudio
AB We reported the first Rh-catalyzed reaction of a diazoacetyl compound with aldehydes that affords thiiranes, instead of oxiranes, as known before. This unusual reactivity relied on the use of N-(diazoacetyl)oxazolidin-2-thiones as new chiral sulfur-donor reagents and enabled the direct production of optically active thiiranes with very high stereoselectivity.
PB Wiley
SN 1433-7851
YR 2012
FD 2012
LK https://hdl.handle.net/20.500.14352/93578
UL https://hdl.handle.net/20.500.14352/93578
LA eng
NO I. Cano, E. Gómez-Bengoa, A. Landa, M. Maestro, A. Mielgo, I. Olaizola, M. Oiarbide, C. Palomo. N-(Diazoacetyl)oxazolidin-2-thiones as sulfur donor reagents: Asymmetric synthesis of thiiranes from aldehydes. Angew. Chem., Int. Ed. 2012, 51, 10856-10860
NO Eusko Jaurlaritza
NO Ministerio de Ciencia, Innovación y Universidades (España)
NO European Commission
DS Docta Complutense
RD 7 oct 2024