TY - JOUR AU - Gutiérrez Casares, José Ramón AU - Quintero Gutiérrez Del Álamo, Francisco Javier AU - Montoto, Carmen PY - 2021 DO - 10.3389/fpsyt.2021.741170 SN - 1664-0640 UR - https://hdl.handle.net/20.500.14352/99000 T2 - Frontiers in Psychiatry AB - Regulatory agencies encourage computer modeling and simulation to reduce the time and cost of clinical trials. Although still not classified in formal guidelines, system biology-based models represent a powerful tool for generating hypotheses with... LA - eng M2 - 1 PB - Frontiers KW - attention-deficit/hyperactivity disorder KW - in silico clinical trial KW - lisdexamfetamine KW - mathematical modeling KW - methylphenidate TI - Methods to Develop an in silico Clinical Trial: Computational Head-to-Head Comparison of Lisdexamfetamine and Methylphenidate T2 - Métodos para desarrollar un ensayo clínico in silico: Comparación computacional directa de lisdexanfetamina y metilfenidato TY - journal article VL - 12 ER -