TY - JOUR AU - Hui, Ye AU - Chaobo, Chen AU - Hanghang, Wu AU - Kang, Zheng AU - Martín Adrados, Beatriz AU - Caparros, Esther AU - Francés, Rubén AU - Nelson, Leonard J. AU - Gómez Del Moral Martín-Consuegra, Manuel María AU - Asensio, Iris AU - Javier Vaquero AU - Bañares Cañizares, Rafael AU - Ávila, Matías A. AU - Andrade, Raúl J. AU - Lucena, María Isabel AU - Martínez Chantar, Maria Luz AU - Reeves, Helen L. AU - Masson, Steven AU - Blumberg, Richard S. AU - Gracia Sancho, Jordi AU - Nevzorova, Yulia AU - Martínez Naves, Eduardo AU - Cubero Palero, Francisco Javier PY - 2022 DO - 10.1038/s41419-022-04580-8 SN - 2041-4889 UR - https://hdl.handle.net/20.500.14352/92253 T2 - Cell Death and Disease AB - Acetaminophen (APAP) hepatotoxicity induces endoplasmic reticulum (ER) stress which triggers the unfolded protein response (UPR) in hepatocytes. However, the mechanisms underlying ER stress remain poorly understood, thus reducing the options for... LA - eng PB - Springer Nature TI - Genetic and pharmacological inhibition of XBP1 protects against APAP hepatotoxicity through the activation of autophagy TY - journal article VL - 13 ER -