RT Journal Article
T1 In vitro activity of mupirocin and amoxicillin-clavulanate alone and in combination against staphylococci including those resistant to methicillin
A1 Alou Cervera, Luis
A1 Cafini, Fabio
A1 Sevillano Fernández, David
A1 Unzueta, Irune
A1 Prieto Prieto, José
AB Mupirocin and amoxicillin-clavulanate were synergistic against 9 of 49 (18%) strains of methicillin-resistant and methicillin-susceptible Staphylococcus aureus and coagulase-negative staphylococci (CNS). A pattern of enhanced killing was also found using time-kill studies. Time-kill assays were more discriminatory than chequerboard titration assays in demonstrating synergy. These results suggest that combinations of amoxicillin-clavulanate and mupirocin may have therapeutic benefits in prophylaxis against staphylococcal infections.
PB Elsevier
SN 0924-8579
YR 2004
FD 2004-05
LK https://hdl.handle.net/20.500.14352/107056
UL https://hdl.handle.net/20.500.14352/107056
LA eng
NO Alou L, Cafini F, Sevillano D, Unzueta I, Prieto J. In vitro activity of mupirocin and amoxicillin-clavulanate alone and in combination against staphylococci including those resistant to methicillin. Int J Antimicrob Agents. 2004 May;23(5):513-6.
DS Docta Complutense
RD 10 abr 2025