RT Journal Article
T1 Dietary Intake of Cadmium, Lead and Mercury and Its Association with Bone Health in Healthy Premenopausal Women
A1 Lavado-García, Jesus
A1 Puerto-Parejo, Luis
A1 Roncero-Martín, Raul
A1 Moran, Jose
A1 Pedrera-Zamorano, Juan
A1 Aliaga Vera, Ignacio
A1 Leal-Hernández, Olga
A1 Canal-Macias, Maria
AB The bone is one of the relevant target organs of heavy metals, and heavy metal toxicity is associated with several degenerative processes, such osteoporosis and bone mineral alterations, that could lead to fractures. We aimed to study a presumed relationship between bone density, evaluated by quantitative bone ultrasound (QUS), dual-energy X-ray absorptiometry (DXA) and peripheral quantitative computed tomography (pQCT) and the dietary intake of cadmium, lead and mercury in healthy premenopausal women. A total of 158 healthy, non-smoking, premenopausal women were incorporated into the study. A validated food frequency questionnaire (FFQ) was administered to assess intake during the preceding seven days. The median predicted dietary cadmium intake among the 158 women studied was 25.29 µg/day (18.62–35.00) and 2.74 µg/kg body weight/week (b.w./w) (1.92–3.83). Dietary lead intake was 43.85 µg/day (35.09–51.45) and 4.82 µg/kg b.w./w (3.67–6.13). The observed dietary mercury intake was 9.55 µg/day (7.18–13.57) and 1.02 µg/kg b.w./w (0.71–1.48). Comparisons, in terms of heavy metal intake, showed no significant results after further adjusting for energy intake. No statistically significant correlations between heavy metal intake and the QUS, DXA and pQCT parameters were observed. Levels of dietary exposure of cadmium, lead and mercury were mostly within the recommendations. We did not find associations between the QUS, DXA and pQCT parameters and the dietary intake of the studied heavy metals in healthy premenopausal women.
PB MDPI
SN 1660-4601
YR 2017
FD 2017
LK https://hdl.handle.net/20.500.14352/19101
UL https://hdl.handle.net/20.500.14352/19101
LA eng
NO Junta de Extremadura
DS Docta Complutense
RD 4 may 2024