%0 Journal Article
%A Urmeneta Ulloa, Javier
%A Pozo Osinalde, Eduardo
%A Rodríguez-Hernández, Juan Lizandro
%A Martínez Fernández, Hugo
%A Islas, Fabián
%A Agustín, Alberto de
%A Marcos-Alberca, Pedro
%A Mahía, Patricia
%A Cobos, Miguel Ángel
%A Hernández Mateo, Paula
%A Cabrera, José Ángel
%A Luaces Méndez, María
%A Gómez de Diego, José Juan
%A Bustos García De Castro, Ana María
%A Macaya Miguel, Carlos
%A Pérez De Isla, Leopoldo
%T Myocardial strain in nonischemic dilated cardiomyopathy with feature tracking. Feasibility and prognostic implications
%D 2020
%U https://hdl.handle.net/20.500.14352/133633
%X Introduction and objectives: Myocardial strain analysis could provide additional information to leftventricular ejection fraction (LVEF) in nonischemic dilated cardiomyopathy (NIDC). Our aim was toanalyze the feasibility of left ventricular strain evaluation using cardiac magnetic resonance featuretracking (FT) in NIDC, and to determine its clinical and prognostic impact.Methods: We retrospectively included consecutive patients with NIDC who underwent cardiac magneticresonance. Left ventricular global longitudinal, circumferential and radial strain were obtained fromstandard cine sequences using FT analysis software. We evaluated their association with a compositeendpoint (heart failure, implantable cardioverter-defibrillator in secondary prevention, or death).Results: FT analysis could be performed in all of the 98 patients (mean age 68  13 years, 72% men). Intraand interobserver concordance was good for global longitudinal and circumferential strain but was worse forradial strain. Global circumferential strain was independently associated (OR, 1.16; P = .045) with LVEFnormalization during follow-up and was the only morphological parameter independently associated withthe composite endpoint (OR, 1.15; P = .038). A cutoff value < 8.2% was able to predict the incidence of thisevent during follow-up (log-rank 4.6; P = .032).Conclusions: Left ventricular strain analysis with FT is feasible and reproducible in NIDC. Globalcircumferential strain was able to predict LVEF recovery and the appearance of major cardiovascularevents during follow-up
%~