RT Journal Article
T1 Mesoporous Silica Nanoparticles as Theranostic Antitumoral Nanomedicine
A1 Baeza, Alejandro
A1 Vallet Regí, María Dulce Nombre
AB Nanoparticles have become a powerful tool in oncology not only as carrier of the highly toxic chemotherapeutic drugs but also as imaging contrast agents that provide valuable information about the state of the disease and its progression. The enhanced permeation and retention effect for loaded nanocarriers in tumors allow substantial improvement of selectivity and safety of anticancer nanomedicines. Additionally, the possibility to design stimuli-responsive nanocarriers able to release their payload in response to specific stimuli provide an excellent control on the administered dosage. The aim of this review is not to present a comprehensive revision of the different theranostic mesoporous silica nanoparticles (MSN) which have been published in the recent years but just to describe a few selected examples to offer a panoramic view to the reader about the suitability and effectiveness of these nanocarriers in the oncology field.
PB MDPI
SN 1999-4923
YR 2020
FD 2020-10-11
LK https://hdl.handle.net/20.500.14352/6636
UL https://hdl.handle.net/20.500.14352/6636
LA eng
NO RESEARCHER ID K-8193-2014  (Alejandro Baeza)ORCID 0000-0002-2026-6266 (Alejandro Baeza)RESEARCHER ID M-3378-2014 (María Vallet Regí)ORCID 0000-0002-6104-4889 (María Vallet Regí)
NO Unión Europea. Horizonte 2020
NO Ministerio de Ciencia e Innovación (MICINN)
DS Docta Complutense
RD 17 may 2024