RT Journal Article
T1 Development of the human temporomandibular joint
A1 Mérida Velasco, José Ramón
A1 Rodríguez Vázquez, José Francisco
A1 Mérida Velasco, Juan A.
A1 Sánchez Montesinos, Indalecio
A1 Espín Ferra, J.
A1 Jiménez Collado, Juan
AB A great deal of research has been published on the development of the human temporomandibular joint (TMJ). However, there is some discordance about its morphological timing. The most controversial aspects concern the moment of the initial organization of the condyle and the squamous part of the temporal bone, the articular disc and capsule and also the cavitation and onset of condylar chondrogenesis.Serial sections of 70 human specimens between weeks 7 and 17 of development were studied by optical microscopy (25 embryos and 45 fetuses). All specimens were obtained from collections of the Institute of Embryology of the Complutense University of Madrid and the Department of Morphological Sciences of the University of Granada.Three phases in the development of the TMJ were identified. The first is the blastematic stage (weeks 7–8 of development), which corresponds with the onset of the organization of the condyle and the articular disc and capsule. During week 8 intramembranous ossification of the temporal squamous bone begins. The second stage is the cavitation stage (weeks 9–11 of development), corresponding to the initial formation of the inferior joint cavity (week 9) and the start condylar chondrogenesis. Week 11 marks the initiation of organization of the superior joint cavity. And the third stage is the maturation stage (after week 12 of development).This work establishes three phases in TMJ development: 1) the blastematic stage (weeks 7–8 of development); 2) the cavitation stage (weeks 9–11 of development); and 3) the maturation stage (after week 12 of development). This study identifies the critical period of TMJ morphogenesis as occurring between weeks 7 and 11 of development.
PB Wiley
SN 1932-8486
YR 1999
FD 1999-11-20
LK https://hdl.handle.net/20.500.14352/122523
UL https://hdl.handle.net/20.500.14352/122523
LA eng
NO Mérida-Velasco, J. R., Rodríguez-Vázquez, J. F., Mérida-Velasco, J. A., Sánchez-Montesinos, I., Espín-Ferra, J., & Jiménez-Collado, J. (1999). Development of the human temporomandibular joint. The Anatomical record, 255(1), 20–33. https://doi.org/10.1002/(SICI)1097-0185(19990501)255:1<20::AID-AR4>3.0.CO;2-N
DS Docta Complutense
RD 26 feb 2026