TY - JOUR AU - Navarro Dorado, Jorge AU - Climent Flórez, Belén AU - López-Oliva Muñoz, María Elvira AU - Martínez Sainz, María Del Pilar AU - Hernández Martín, Marina AU - Agis Torres, Ángel AU - Recio Visedo, María Paz AU - Barahona Gomáriz, María Victoria AU - Benedito Castellote, Sara AU - Leite Fernandes, Vitor Samuel AU - Hernández Rodríguez, Medardo Vicente PY - 2023 DO - 10.1016/j.bcp.2023.115754 SN - 0006-2952 UR - https://hdl.handle.net/20.500.14352/91742 T2 - Biochemical Pharmacology AB - Bitter taste receptors (TAS2R) are found in numerous extra-oral tissues, including smooth muscle (SM) cells in both vascular and visceral tissues. Upon activation, TAS2R stimulate the relaxation of the SM. Nitric oxide (NO)/cyclic guanosine... LA - eng M2 - 115754 PB - Elsevier KW - Bitter taste receptors KW - Denatonium KW - Rat corpus cavernosum KW - Smooth muscle relaxation KW - TAS2R agonists TI - The bitter taste receptor (TAS2R) agonist denatonium promotes a strong relaxation of rat corpus cavernosum TY - journal article VL - 215 ER -