RT Journal Article T1 The ESCRT machinery: new roles at new holes A1 Olmos Buchelt, Yolanda A1 Carlton, J.G. AB The ESCRT machinery drives a diverse collection of membrane remodeling events, including multivesicular body biogenesis, release of enveloped retroviruses and both reformation of the nuclear envelope and cytokinetic abscission during mitotic exit. These events share the requirement for a topologically equivalent membrane remodeling for their completion and the cells deployment of the ESCRT machinery in these different contexts highlights its functionality as a transposable membrane-fission machinery. Here, we will examine recent data describing ESCRT-III dependent membrane remodeling and explore new roles for the ESCRT-III complex at the nuclear envelope. PB Elsevier YR 2016 FD 2016-01-15 LK https://hdl.handle.net/20.500.14352/105009 UL https://hdl.handle.net/20.500.14352/105009 LA eng NO Olmos Y, Carlton J. The ESCRT machinery: new roles at new holes. Current Opinion in Cell Biology. 2016;38:1-11. NO Grant 093603/Z/10/Z NO Wellcome Trust (United Kingdom) DS Docta Complutense RD 11 abr 2025