RT Journal Article
T1 Paroxysmal headache with extracephalic irradiation: Proposal for a new variant of epicrania fugax in a series of five patients
A1 Gutiérrez Sánchez, María Mercedes
A1 García Azorín, David
A1 Gutiérrez Viedma, Álvaro
A1 González García, Nuria
A1 Horga, Alejandro
A1 Martín, Susana
A1 Guerrero, Ángel L
A1 Cuadrado Pérez, María De La Luz
A2 Sage, 
AB Background Epicrania fugax consists of brief paroxysms of pain, which radiate in a line or in zigzag trajectory across the surface of the scalp or the face. Methods A prospective, descriptive study was performed in five patients presenting with an epicrania fugax-type pain with extracephalic irradiation. Results All patients were women, and the mean age at onset was 59.8 (standard deviation, 10.9). They had unilateral paroxysms of electrical pain starting at a particular point in the head (parietal, n = 3; vertex, n = 1; frontal, n = 1) and rapidly radiating downwards in a lineal trajectory to reach extracephalic regions (ipsilateral limbs, n = 2; shoulder, n = 2; low neck, n = 1) in 1–3 seconds. Pain intensity was moderate or severe. Three patients had nummular headache at the point where the paroxysms originated. One patient had spontaneous remission, and four patients achieved complete or almost complete response with therapy (onabotulinumtoxinA, n = 2; indomethacin, n = 1; amitriptyline, n = 1; lamotrigine, n = 1). Conclusion The spectrum of epicrania fugax may include paroxysms with extracephalic irradiation. The propagation of pain beyond the head and the face supports the involvement of central mechanisms in the pathophysiology of this entity.
PB Sage
SN 0333-1024
SN 1468-2982
YR 2020
FD 2020-04-15
LK https://hdl.handle.net/20.500.14352/110381
UL https://hdl.handle.net/20.500.14352/110381
LA eng
NO Gutiérrez-Sánchez M, García-Azorín D, Gutiérrez-Viedma Á, González-García N, Horga A, Martín S, Guerrero ÁL, Cuadrado ML. Paroxysmal headache with extracephalic irradiation: Proposal for a new variant of epicrania fugax in a series of five patients. Cephalalgia. 2020 Aug;40(9):959-965.
DS Docta Complutense
RD 27 abr 2025