RT Book, Section T1 CHAPTER 10: Drug Delivery Systems for the Treatment of Diseases Affecting the Retina and Optic Nerve. A1 Bravo Osuna, Irene A1 Andrés Guerrero, Vanesa A1 Molina Martínez, Irene Teresa A1 Herrero Vanrell, María Del Rocío A2 De la Rosa, Enrique A2 Cotter, Thomas AB Diseases affecting the retina and the optic nerve are the major causes of irreversible blindness in the elderly population. Succesful therapy of these pathologies requires frequent administration of the active molecule close to the retinal target site. Intraocular drug delivery systems (IDDS) are emerging therapeutic tools in the treatment of diseases affecting the posterior segment, as they are able to provide effective concentrations of the drug for a long period, thus avoiding successive injections. Depending on their size, IDDS are classified in implants, microsystems and nanosystems. This chapter covers a general description of the IDDS useful for the treatment of diseases affecting retinal structures. © The Royal Society of Chemistry 2019. PB Royal Society of Chemistry SN 978-1-78262-949-8 SN 978-1-78801-366-6 SN 978-1-78801-536-3 YR 2018 FD 2018 LK https://hdl.handle.net/20.500.14352/94041 UL https://hdl.handle.net/20.500.14352/94041 LA eng NO Bravo-Osuna I., Andrés-Guerrero V., Molina-Martínez I.T., Herrero-Vanrell R. CHAPTER 10: Drug Delivery Systems for the Treatment of Diseases Affecting the Retina and Optic Nerve (2019) RSC Drug Discovery Series, 2019-January (66), pp. 164 - 178. DOI: 10.1039/9781788013666-00164. EDITORS: de la Rosa E.J., Cotter T.G. UBLISHER: Royal Society of Chemistry. ISSN: 20413203. NO Título: RSC DRUG DISCOVERY SERIESISSN relacionados: 2041-3211País: United KingdomÁmbito: CIENCIAS MÉDICAS Y DE LA SALUDCampo académico: FARMACOLOGÍA Y FARMACIAIndizada en: Scopus (ELSEVIER), EMBASE (ELSEVIER)Métricas en: SJR. SCImago Journal & Country Rank, Scopus Sources NO Ministerio de Ciencia, Innovación y Universidades (España) NO Ministerio de Economía, Comercio y Empresa (España) NO Instituto de Salud Carlos III DS Docta Complutense RD 6 abr 2025