RT Journal Article
T1 Comparison of the Hemodynamic Performance of the Balloon-expandable SAPIEN 3 Versus Self-expandable Evolut R Transcatheter Valve: A Case-matched Study
A1 Enríquez Rodríguez, Eduardo
A1 Amat Santos, Ignacio J.
A1 Jiménez Quevedo, Pilar
A1 Martín Morquecho, Irene
A1 Tirado Conte, Gabriela
A1 Pérez-Vizcayno, María José
A1 Gómez de Diego, José Juan
A1 Arnold, Roman
A1 Aldazábal, Andrés
A1 Rojas, Paol
A1 Agustín, Alberto de
A1 Trigo, María Del
A1 Gutiérrez, Hipólito
A1 San Román, José A.
A1 Macaya Miguel, Carlos
A1 Nombela Franco, Luis
AB Introduction and objectives: The SAPIEN 3 (S3) valve and the Medtronic Evolut R (EVR) are secondgeneration transcatheter valves, designed to further reduce the rate of paravalvular aortic regurgitation(AoR). The aim of this study was to compare the 2 devices in terms of valve performance in a casematched study with independent echocardiographic analysis.Methods: Of a population of 201 patients who underwent transcatheter aortic valve implantation,144 patients (S3, n = 80; EVR, n = 64) were matched according to aortic annulus diameter and aortic valvecalcium score, as assessed by computed tomography. All echocardiographic examinations collected atbaseline and at 1- and 6-month follow-up were centrally analyzed.Results: The 2 groups were well balanced in baseline clinical and echocardiographic characteristics. TheEVR valve showed a better hemodynamic profile as assessed by peak aortic gradient (EVR 13  7 vsS3 20  10 mmHg; P < .001), mean aortic gradient (EVR 7  3 vs S3 11  6 mmHg; P < .001), and Dopplervelocity index (EVR 0.65  0.15 vs S3 0.51  0.16; P < .001). The rate of moderate-severe or any paravalvular( mild) AoR was higher in the EVR group (11% and 50%) than in the S3 group (2.5% and 21%; P < .05,respectively), with a larger number of paravalvular jets (P < .001).Conclusions: In a case-matched cohort of transcatheter aortic valve implantation patients, the S3 valve wasassociatedwitha lower rate ofparavalvularAoR but alsowithahigher residual gradientthanthe EVRsystem.
PB Elsevier
YR 2017
FD 2017-11-28
LK https://hdl.handle.net/20.500.14352/133626
UL https://hdl.handle.net/20.500.14352/133626
LA eng
NO Enríquez-Rodríguez E, Amat-Santos IJ, Jiménez-Quevedo P, Martín-Morquecho I, Tirado-Conte G, Pérez-Vizcayno MJ, et al. Comparación de la hemodinámica valvular de la prótesis transcatéter con balón expandible SAPIEN 3 frente a la autoexpandible Evolut R: estudio de casos emparejados. Revista Española de Cardiología 2018;71:735–42. https://doi.org/10.1016/j.recesp.2017.10.032
DS Docta Complutense
RD 5 mar 2026