TY - JOUR AU - Cordani, Marco AU - Butera, Giovanna AU - Dando, Ilaria AU - Torrens-Mas, Margalida AU - Butturini, Elena AU - Pacchiana, Raffaella AU - Oppici, Elisa AU - Cavallini, Chiara AU - Gasperini, Sara AU - Tamassia, Nicola AU - Nadal-Serrano, Mercedes AU - Coan, Michela AU - Rossi, Davide AU - Gaidano, Gianluca AU - Caraglia, Michele AU - Mariotto, Sofia AU - Spizzo, Riccardo AU - Roca, Pilar AU - Oliver, Jordi AU - Scupoli, Maria Teresa AU - Donadelli, Massimo PY - 2018 DO - 10.1038/s41416-018-0288-2 SN - 0007-0920 UR - https://hdl.handle.net/20.500.14352/94636 T2 - British Journal of Cancer AB - Background. The TP53 tumor suppressor gene is the most frequently altered gene in tumors and mutant p53 gain-of-function isoforms actively promote cancer malignancy.Methods. A panel of wild-type and mutant p53 cancer cell lines of different tissues,... LA - eng M2 - 994 PB - Springer Nature TI - Mutant p53 blocks SESN1/AMPK/PGC-1α/UCP2 axis increasing mitochondrial O2ˉ· production in cancer cells TY - journal article VL - 119 ER -