RT Journal Article
T1 Biological Performance of Duplex PEO + CNT/PCL Coating on AZ31B Mg Alloy for Orthopedic and Dental Applications
A1 Daavari, Morteza
A1 Atapour, Masoud
A1 Mohedano Sánchez, Marta
A1 Matykina, Endzhe
A1 Arrabal Durán, Raúl
AB To regulate the degradation rate and improve the surface biocompatibility of the AZ31B magnesium alloy, three different coating systems were produced via plasma electrolytic oxidation (PEO): simple PEO, PEO incorporating multi-walled carbon nanotubes (PEO + CNT), and a duplex coating that included a polycaprolactone top layer (PEO + CNT/PCL). Surfaces were characterized by chemical content, roughness, topography, and wettability. Biological properties analysis included cell metabolism and adhesion. PEO ± CNT resulted in an augmented surface roughness compared with the base material (BM), while PCL deposition produced the smoothest surface. All surfaces had a contact angle below 90°. The exposure of gFib-TERT and bmMSC to culture media collected after 3 or 24 h did not affect their metabolism. A decrease in metabolic activity of 9% and 14% for bmMSC and of 14% and 29% for gFib-TERT was observed after 3 and 7 days, respectively. All cells died after 7 days of exposure to BM and after 15 days of exposure to coated surfaces. Saos-2 and gFib-TERT adhered poorly to BM, in contrast to bmMSC. All cells on PEO anchored into the pores with filopodia, exhibited tiny adhesion protrusions on PEO + CNT, and presented a web-like spreading with lamellipodia on PEO + CNT/PCL. The smooth and homogenous surface of the duplex PEO + CNT/PCL coating decreased magnesium corrosion and led to better biological functionality.
PB MDPI
SN 2079-4983
YR 2023
FD 2023-09-16
LK https://hdl.handle.net/20.500.14352/105718
UL https://hdl.handle.net/20.500.14352/105718
LA eng
NO Daavari, M.; Atapour, M.; Mohedano, M.; Matykina, E.; Arrabal, R.; Nesic, D. Biological Performance of Duplex PEO + CNT/PCL Coating on AZ31B Mg Alloy for Orthopedic and Dental Applications. J. Funct. Biomater. 2023, 14, 475. https://doi.org/10.3390/jfb14090475
DS Docta Complutense
RD 20 abr 2025