RT Journal Article T1 Selective estrogen receptor modulators as brain therapeutic agents A1 Arévalo, Maria Ángeles A1 Santos-Galindo, Maria A1 Lagunas García, Luisa Natalia A1 Azcoitia Elías, Íñigo A1 Luis M. Garcia-Segura, AB Selective estrogen receptor modulators (SERMs), used for the treatment of breast cancer, osteoporosis, and menopausal symptoms, affect the nervous system. Some SERMs trigger neuroprotective mechanisms and reduce neural damage in different experimental models of neural trauma, brain inflammation, neurodegenerative diseases, cognitive impairment, and affective disorders. New SERMs with specific actions on neurons and glial cells may represent promising therapeutic tools for the brain. PB BioScientifica SN 0952-5041 SN 1479-6813 YR 2010 FD 2010 LK https://hdl.handle.net/20.500.14352/95498 UL https://hdl.handle.net/20.500.14352/95498 LA eng NO Arevalo MA, Santos-Galindo M, Lagunas N, Azcoitia I, Garcia-Segura LM. Selective estrogen receptor modulators as brain therapeutic agents. J Mol Endocrinol. 2011 Jan 19;46(1):R1-9. doi: 10.1677/JME-10-0122. PMID: 21071476. DS Docta Complutense RD 7 abr 2025