RT Journal Article T1 Cognitive Reserve Characteristics and Occupational Performance Implications in People with Mild Cognitive Impairment A1 Mendoza Holgado, Cristina A1 Lavado-Garcia, Jesus A1 López-Espuela, Fidel A1 Roncero-Martin, Raul A1 Canal Macías, María Luz A1 Vera González, Vicente A1 Aliaga Vera, Ignacio Joaquín A1 Rey-Sanchez, Purificacion A1 Pedrera Zamorano, Juan Diego A1 Moran, Jose M. AB The Cognitive Reserve hypothesis suggests that there are individual differences in the ability to cope with the pathologic changes in Alzheimer’s Disease. The proportion of elderly individuals has increased in recent years; this increase emphasizes the importance of early detection of mild cognitive impairment and the promotion of healthy ageing. The purpose of our study is to characterize cognitive reserve and occupational performance implications in people with mild cognitive impairment. 125 patients with mild cognitive impairment were enrolled. The Montreal Cognitive Assessments (MoCA) was used to evaluate cognitive status and the Cognitive Reserve Index Questionnaire (CRIq) as an indicator of cognitive reserve. Higher level of education was associated with higher MoCA scores (r = 0.290, p = 0.001). Positive significant correlations were observed between MoCA and total CRIq (r = 0.385, p < 0.001) as well as its three sub-domains, education (r = 0.231, p = 0.010), working activity (r = 0.237, p = 0.008) and leisure time (r = 0.319, p < 0.001). This study findings provide the importance of considering socio-behavioral factors in cognitive status. This research helps to describe the importance of engaging occupationally along the whole life-course as a potential protective factor in ageing, and includes a perspective of occupational therapy regarding the hypothesis of cognitive reserve. PB MDPI SN 2227-9032 YR 2021 FD 2021-09-26 LK https://hdl.handle.net/20.500.14352/5082 UL https://hdl.handle.net/20.500.14352/5082 LA eng DS Docta Complutense RD 11 abr 2025