RT Journal Article T1 Seeing the invisible: Digital holography A1 Carpio Rodríguez, Ana María AB For the past years there has been an increasing interest in developing mathematical and computational methods for digital holography. Holographic techniques furnish noninvasive tools for high-speed 3D live cell imaging. Holograms can be recorded in the millisecond or microsecond range without damaging samples. A hologram encodes the wave field scattered by an object as an interference pattern. Digital holography aims to create numerical images from digitally recorded holograms. We show here that partial differential equation constrained optimization, topological derivatives of shape functionals, iteratively regularized Gauss–Newton methods, Bayesian inference, and Markov chain Monte Carlo techniques provide effective mathematical tools to invert holographic data with quantified uncertainty. Holography set-ups are particularly challenging because a single incident wave is employed. Similar tools could be useful in inverse scattering problems involving other types of waves and different emitter/receiver configurations, such as microwave imaging or elastography, for instance. PB European Mathematical Society SN 2747-7894 YR 2022 FD 2022 LK https://hdl.handle.net/20.500.14352/72005 UL https://hdl.handle.net/20.500.14352/72005 LA eng NO Carpio Rodríguez, A. M. «Seeing the invisible: Digital holography». European Mathematical Society Magazine, n.o 125, septiembre de 2022, pp. 4-12. DOI.org (Crossref), https://doi.org/10.4171/mag/99. NO Ministerio de Ciencia, Innovación y Universidades (España)/Fondo Europeo de Desarrollo Regional NO Fundación Caja Madrid Mobility grants, and MICINN “Salvador de Madariaga” Mobility DS Docta Complutense RD 11 may 2025