TY  - JOUR
AU  - Ceballos-Garzón, Andrés
AU  - Román González, Elvira
AU  - Pla Alonso, Jesús
AU  - Pagniez, Fabrice
AU  - Amado, Daniela
AU  - Alméciga-Díaz, Carlos
AU  - Le Pape, Patrice
AU  - Parra Giraldo, Claudia Marcela
PY  - 2022
DO  - 10.1371/journal.pone.0265777
UR  - https://hdl.handle.net/20.500.14352/128922
T2  - PloSOne
AB  - nvasive fungal infections, which kill more than 1.6 million patients each year worldwide, are difficult to treat due to the limited number of antifungal drugs (azoles, echinocandins, and polyenes) and the emergence of antifungal resistance. The...
LA  - eng
KW  - Candida glabrata
KW  - antigungals
KW  - Crz1
KW  - equinocandin
KW  - CRISPR
KW  - virulence
TI  - CRISPR-Cas9 approach confirms Calcineurin-responsive zinc finger 1 (Crz1) transcription factor as a promising therapeutic target in echinocandin-resistant Candida glabrata
TY  - journal article
VL  - 17
ER  -