RT Journal Article
T1 Increased Systemic Malondialdehyde Levels and Decreased Mo/Co, Co/Fe2+ Ratios in Patients with Long-Term Dental Titanium Implants and Amalgams
A1 Merino Martín, José Joaquín
A1 Cabaña-Muñoz, María Eugenia
A1 Parmigiani-Izquierdo, José María
A1 Camacho Alonso, Fabio
AB AbstractIntroduction: the biological safety of dental biomaterials has been questioned in human studies.Material and methods: Several heavy metals/oligoelements were compared by Inductive Coupled Mass Spectrometry (ICP-MS) in hair samples from 130 patients (n = 54 patients with long-term titanium dental implants and amalgams (A + I group), 51 patients with long-term dental amalgam alone (A group), as well as controls (n = 25: without dental materials) of similar age. All patients (except controls) had had titanium dental implants and/or dental amalgams for at least 10 years (average: 17). We evaluated whether A + I patients could present higher systemic malondialdehyde levels (MDA) as compared to the A group.Results: The A + I group have lower molybdenum levels (A + I) and reduced Mo/Co and Mo/Fe2+ ratios, which could predispose them to oxidative stress by raising MDA levels as compared to the A group alone; our findings suggest that higher Co levels could enhance oxidative stress in the A + I group. However, there were no differences on metals from titanium alloy (Ti-6Al), Cr from crowns or Hg2+, Sn, Zn2+, Cu2+ levels between the A + I and A groups.Conclusion: patients with long-term dental titanium and amalgams have systemic oxidative stress due to rising MDA levels and lower Mo/Co and Mo/Fe2+ ratios than those with amalgams alone.
PB MDPI
YR 2019
FD 2019
LK https://hdl.handle.net/20.500.14352/116385
UL https://hdl.handle.net/20.500.14352/116385
LA eng
NO Cabaña-Muñoz, María Eugenia, et al. «Increased Systemic Malondialdehyde Levels and Decreased Mo/Co, Co/Fe2+ Ratios in Patients with Long-Term Dental Titanium Implants and Amalgams». Journal of Clinical Medicine, vol. 8, n.o 1, enero de 2019, p. 86. DOI.org (Crossref), https://doi.org/10.3390/jcm8010086.
NO Centro de Implantología y Rehabilitación Oral Multidisciplinaria (España)
DS Docta Complutense
RD 15 abr 2025