%0 Journal Article
%A Roscales García, Silvia
%A García Csaky, Aurelio
%T Trifluoroacetic anhydride promoted tandem conjugate addition of boronic acids/acetal ring opening
%D 2012
%U https://hdl.handle.net/20.500.14352/114679
%X A new stereoselective tandem reaction consisting of the metal-free conjugate addition of boronic acids followed by an intramolecular ring opening of a cyclic acetal has been disclosed. Optically pure polysubstituted tetrahydropyrans have been synthesized diastereoselectively by this new reaction. Two new C–C bonds and up to three stereocenters are formed in a single step, allowing the generation of quaternary stereocenters.
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