%0 Journal Article
%A Lorente Pérez, María Del Mar
%A Torres, Sofia
%A Salazar Roa, María
%A Carracedo, Arkaitz
%A Hernández Tiedra, Sonia
%A Rodríguez Fornés, Fátima
%A García Taboada, Elena
%A Meléndez, Bárbara
%A Mollejo, Manuela
%A Campos Martín, Yolanda
%A Barcia Albacar, Juan Antonio
%A Guzmán Pastor, Manuel
%A Velasco Díez, Guillermo
%T Stimulation of ALK by the growth factor midkine renders glioma cells resistant to autophagy-mediated cell death
%D 2011
%@ 1554-8627
%U https://hdl.handle.net/20.500.14352/97335
%X Δ9-tetrahydrocannabinol (THC), the main active component of marijuana, promotes cancer cell death via autophagy stimulation. We find that activation of the tyrosine kinase receptor ALK by its ligand midkine interferes with the signaling mechanism by which THC promotes autophagy-mediated glioma cell death.
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