RT Journal Article
T1 Stimulation of ALK by the growth factor midkine renders glioma cells resistant to autophagy-mediated cell death
A1 Lorente Pérez, María Del Mar
A1 Torres, Sofia
A1 Salazar Roa, María
A1 Carracedo, Arkaitz
A1 Hernández Tiedra, Sonia
A1 Rodríguez Fornés, Fátima
A1 García Taboada, Elena
A1 Meléndez, Bárbara
A1 Mollejo, Manuela
A1 Campos Martín, Yolanda
A1 Barcia Albacar, Juan Antonio
A1 Guzmán Pastor, Manuel
A1 Velasco Díez, Guillermo
AB Δ9-tetrahydrocannabinol (THC), the main active component of marijuana, promotes cancer cell death via autophagy stimulation. We find that activation of the tyrosine kinase receptor ALK by its ligand midkine interferes with the signaling mechanism by which THC promotes autophagy-mediated glioma cell death.
PB Taylor & Francis 
SN 1554-8627
YR 2011
FD 2011
LK https://hdl.handle.net/20.500.14352/97335
UL https://hdl.handle.net/20.500.14352/97335
LA eng
NO Lorente, M., Torres, S., Salazar, M., Carracedo, A., Hernández-Tiedra, S., Rodríguez-Fornés, F., … Velasco, G. (2011). Stimulation of ALK by the growth factor midkine renders glioma cells resistant to autophagy-mediated cell death. Autophagy, 7(9), 1071–1073. https://doi.org/10.4161/auto.7.9.15866
DS Docta Complutense
RD 8 abr 2025