TY  - JOUR
AU  - Fiorini, Claudia
AU  - Cordani, Marco
AU  - Gotte, Giovanni
AU  - Picone, Delia
AU  - Donadelli, Massimo
PY  - 2015
DO  - 10.1016/j.bbamcr.2014.12.016
SN  - 0167-4889
UR  - https://hdl.handle.net/20.500.14352/97283
T2  - Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
AB  - Onconase® (ONC) is a member of the RNase super-family that is secreted in oocytes and early embryos of Rana pipiens. Over the last years, research interest about this small and basic frog RNase, also called ranpirnase, constantly increased because of...
LA  - eng
M2  - 549
PB  - Elsevier
KW  - Autophagy
KW  - Onconase
KW  - Pancreatic cancer
KW  - Reactive oxygen species (ROS)
KW  - Mammalian target of rapamycin (mTOR)
KW  - Gemcitabine
TI  - Onconase induces autophagy sensitizing pancreatic cancer cells to gemcitabine and activates Akt/mTOR pathway in a ROS-dependent manner
TY  - journal article
VL  - 1853
ER  -