RT Journal Article
T1 Assembly of glycoamino acid building blocks: a new strategy for the straightforward synthesis of heparan sulfate mimics
T2 Inglés
A1 Revuelta, Julia
A1 Fuentes, Roberto
A1 Lagartera, Laura
A1 Hernáiz Gómez-Degano, María Josefa
A1 Bastida, Agatha
A1 García-Junceda, Eduardo
A1 Fernández-Mayoralas, Alfonso
AB A new strategy that enables a modular straightforward synthesis of heparan sulfate oligosaccharide mimics by the assembly of simple glycoamino acid building blocks is described. The coupling between units is readily carried out by an amidation reaction. Several glycoamino acid oligomers were prepared and their interaction with the FGF2 protein was analyzed.
PB Royal Society of Chemistry
SN 1359-7345
YR 2018
FD 2018
LK https://hdl.handle.net/20.500.14352/95778
UL https://hdl.handle.net/20.500.14352/95778
LA eng
NO Revuelta J, Fuentes R, Lagartera L, Hernáiz MJ, Bastida A, García-Junceda E, et al. Assembly of glycoamino acid building blocks: a new strategy for the straightforward synthesis of heparan sulfate mimics. Chem Commun 2018;54:13455–8. https://doi.org/10.1039/C8CC08067D.
NO Ministerio de Economía y Competitividad (España)
DS Docta Complutense
RD 8 jul 2025