TY  - JOUR
AU  - Cordani, Marco
AU  - Oppici, Elisa 
AU  - Dando, Ilaria 
AU  - Butturini, Elena 
AU  - Dalla Pozza, Elisa 
AU  - Nadal-Serrano, Mercedes 
AU  - Oliver, Jordi 
AU  - Roca, Pilar 
AU  - Mariotto, Sofia 
AU  - Cellini, Barbara 
AU  - Blandino, Giovanni 
AU  - Palmieri, Marta 
AU  - Di Agostino, Silvia 
AU  - Donadelli, Massimo 
PY  - 2016
DO  - 10.1016/j.molonc.2016.04.001
SN  - 1878-0261
UR  - https://hdl.handle.net/20.500.14352/94638
T2  - Molecular Oncology
AB  - Mutations in TP53 gene play a pivotal role in tumorigenesis and cancer development. Here, we report that gain-of-function mutant p53 proteins inhibit the autophagic pathway favoring antiapoptotic effects as well as proliferation of pancreas and breast...
LA  - eng
M2  - 1008
PB  - FEBS Press
KW  - Autophagy
KW  - Mutant p53
KW  - Gain-of-function
KW  - Cancer
KW  - mTOR
KW  - AMPK
TI  - Mutant p53 proteins counteract autophagic mechanism sensitizing cancer cells to mTOR inhibition
TY  - journal article
VL  - 10
ER  -