TY - JOUR AU - Chalmers, James D. AU - Metersky, Mark L. AU - Puente Maestu, Luis PY - 2025 DO - 10.1056/NEJMoa2411664 SN - 0028-4793 UR - https://hdl.handle.net/20.500.14352/129982 T2 - N Engl J Med. AB - BACKGROUND: In bronchiectasis, neutrophilic inflammation is associated with an increased risk of exacerbations and disease progression. Brensocatib, an oral, reversible inhibitor of dipeptidyl peptidase 1 (DPP-1), targets neutrophil serine proteases,... LA - eng M2 - 1569 PB - Massachusetts Medical Society KW - Bronchiectasis KW - DPP-1 Inhibitor Brensocatib TI - Phase3 Trial of the DPP-1 Inhibitor Brensocatib in Bronchiectasis TY - journal article VL - 392 ER -