RT Journal Article T1 Usefulness of implementing the OHIP-14 questionnaire to assess the impact of xerostomia and hyposalivation on qualityof life in patients with primary Sjögren's syndrome A1 Serrano Valle, Julia A1 López-Pintor Muñoz, Rosa María A1 Fernández Castro, Mónica A1 Ramírez Martínez-Acitores, Lucía A1 Sanz Alonso, Mariano A1 López, Javier A1 Blázquez, María Angeles A1 González, Jorge Juan A1 Hernández Vallejo, Gonzalo AB Background: The aim of this study is to analyze if the results of the Oral Health Impact Profile-14 questionnaire (OHIP-14) in patients with primary Sjögren's syndrome (pSS) are correlated with salivary flow and level of xerostomia.Methods: This observational cross-sectional study was conducted in 61 patients (60 women, one man, mean age 57.64 [13.52]) diagnosed of pSS according to the American-European Criteria (2002). After recording demographic, medical and dental data (decayed-missing-filled teeth index [DMFT]), unstimulated (UWS) and stimulated (SWS) salivary flows were collected. Subsequently, UWS flow was categorized into two groups (0.7 ml/min). Patients also filled out a visual analog scale (VAS) for xerostomia and OHIP-14 for self-reported quality of life (QoL). Results: Data showed positive and significant correlation between OHIP-14 and xerostomia, based on VAS results (r = 0.52; p = 0.001). Furthermore, there was a negative correlation between UWS and OHIP-14 scores (r = -0.34; p = 0.006) and VAS for xerostomia (r = -0.22; p = 0.09). No significant correlation was found between SWS and OHIP-14 or VAS neither between DMFT and OHIP-14. When assessing the level of QoL by the UWS and SWS flow categories a significant association was found for UWS (p = 0.001) but not for SWS (p = 0.11). The OHIP-14 values were higher in the groups with lower salivary flow. The multiple linear regression to predict OHIP-14 only selected VAS for xerostomia as a statistically significant predictor. Conclusions: Increased level of xerostomia and reduced UWS flow decrease oral health-related QoL in patients with pSS. PB Wiley SN 1600-0714 YR 2022 FD 2022-08-23 LK https://hdl.handle.net/20.500.14352/72104 UL https://hdl.handle.net/20.500.14352/72104 LA eng NO CRUE-CSIC (Acuerdos Transformativos 2022) DS Docta Complutense RD 28 sept 2024