TY  - JOUR
AU  - Amorós García, Irene
AU  - Dolz Gaitón, Pablo
AU  - Gómez García, Ricardo
AU  - Matamoros, Marcos
AU  - Barana Muñoz, Adriana
AU  - González de la Fuente, Marta
AU  - Núñez, Mercedes
AU  - Pérez Hernández, Marta
AU  - Moraleda, Ignacio
AU  - Gálvez Ruano, Enrique
AU  - Iriepa, Isabel
AU  - Tamargo Menéndez, Juan
AU  - Caballero Collado, Ricardo
AU  - Delpón Mosquera, María Eva
PY  - 2013
DO  - 10.1016/j.bcp.2013.04.023
SN  - 0006-2952
UR  - https://hdl.handle.net/20.500.14352/100150
T2  - Biochemical Pharmacology
AB  - Human cardiac inward rectifier current (IK1) is generated by Kir2.x channels. Inhibition of IK1 could offer a useful antiarrhythmic strategy against fibrillatory arrhythmias. Therefore, elucidation of Kir2.x channels pharmacology, which still remains...
LA  - eng
M2  - 267
PB  - Elsevier
KW  - Propafenone
KW  - Human atrial myocytes
KW  - IK1
KW  - PIP2
KW  - Rectification
KW  - Inward rectifier channels
TI  - Propafenone blocks human cardiac Kir2.x channels by decreasing the negative electrostatic charge in the cytoplasmic pore
TY  - journal article
VL  - 86
ER  -