%0 Journal Article
%A Bosch-Morell, Francisco
%A Villagrasa Sebastián, Victoria
%A Ortega Hernández-Agero, María Teresa
%A Acero De Mesa, Nuria
%A Muñoz-Mingarro, María Dolores
%A González Rosende, Eugenia
%A Castillo García, Encarna
%A Sanhauja Santafé, María Amparo
%A Soriano Guarinos, Pilar
%A Martínez-Solís, Isabel
%T Medicinal plants and natural products as neuroprotective agents in age-related macular degeneration
%D 2020
%@ 1673-5374
%U https://hdl.handle.net/20.500.14352/100298
%X The retina may suffer neurodegenerative damages, as other tissues of the central nervous system do, and serious eye diseases may develop. One of them is age-related macular degeneration, which causes progressive loss of vision due to retina degeneration. Treatment of age-related macular degeneration focuses on antioxidant agents and anti-vascular endothelial growth factor compounds, among others, that prevent/diminish oxidative stress and reduce neovascularisation respectively. The phytochemicals, medicinal plants and/or plant-diet supplements might be a useful adjunct in prevention or treatment of age-related macular degeneration owing to their antioxidant and anti-vascular endothelial growth factor properties. This review article presents the most investigated plants and natural products in relation to age-related macular degeneration, such as saffron, ginkgo, bilberry and blueberry, curcuma or turmeric, carotenoids, polyphenols, and vitamins C and E. This study provides up-to-date information on the effects, treatments, safety and efficiency of these phytotherapy products.
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