RT Journal Article
T1 Medicinal plants and natural products as neuroprotective agents in age-related macular degeneration
A1 Bosch-Morell, Francisco
A1 Villagrasa Sebastián, Victoria
A1 Ortega Hernández-Agero, María Teresa
A1 Acero De Mesa, Nuria
A1 Muñoz-Mingarro, María Dolores
A1 González Rosende, Eugenia
A1 Castillo García, Encarna
A1 Sanhauja Santafé, María Amparo
A1 Soriano Guarinos, Pilar
A1 Martínez-Solís, Isabel
AB The retina may suffer neurodegenerative damages, as other tissues of the central nervous system do, and serious eye diseases may develop. One of them is age-related macular degeneration, which causes progressive loss of vision due to retina degeneration. Treatment of age-related macular degeneration focuses on antioxidant agents and anti-vascular endothelial growth factor compounds, among others, that prevent/diminish oxidative stress and reduce neovascularisation respectively. The phytochemicals, medicinal plants and/or plant-diet supplements might be a useful adjunct in prevention or treatment of age-related macular degeneration owing to their antioxidant and anti-vascular endothelial growth factor properties. This review article presents the most investigated plants and natural products in relation to age-related macular degeneration, such as saffron, ginkgo, bilberry and blueberry, curcuma or turmeric, carotenoids, polyphenols, and vitamins C and E. This study provides up-to-date information on the effects, treatments, safety and efficiency of these phytotherapy products.
PB Wolters Kluwer – Medknow
SN 1673-5374
YR 2020
FD 2020
LK https://hdl.handle.net/20.500.14352/100298
UL https://hdl.handle.net/20.500.14352/100298
LA eng
NO 'Bosch-Morell F, Villagrasa V, Ortega T, Acero N, Muñoz-Mingarro D, González-Rosende ME, Castillo E, Sanahuja MA, Soriano P, Martínez-Solís I. Medicinal plants and natural products as neuroprotective agents in age-related macular degeneration. Neural Regen Res. 2020 Dec;15(12):2207-2216'
DS Docta Complutense
RD 26 dic 2025