RT Journal Article T1 First Detection of SARS-CoV-2 B.1.1.7 Variant of Concern in an Asymptomatic Dog in Spain A1 Barroso Arévalo, Sandra A1 Sánchez-Vizcaíno Rodríguez, José Manuel A1 Domínguez Rodríguez, Lucas José A1 Rivera Arroyo, Belén AB Natural SARS-CoV-2 infection in pets has been widely documented during the last year. Although the majority of reports suggested that dogs’ susceptibility to the infection is low, little is known about viral pathogenicity and transmissibility in the case of variants of concern, such as B.1.1.7 in this species. Here, as part of a large-scale study on SARS-CoV-2 prevalence in pets in Spain, we have detected the B.1.1.7 variant of concern (VOC) in a dog whose owners were infected with SARS-CoV-2. The animal did not present any symptoms, but viral loads were high in the nasal and rectal swabs. In addition, viral isolation was possible from both swabs, demonstrating that the dog was shedding infectious virus. Seroconversion occurred 23 days after the first sampling. This study documents the first detection of B.1.1.7 VOC in a dog in Spain and emphasizes the importance of performing active surveillance and genomic investigation on infected animals. PB MPDI SN 1999-4915 YR 2021 FD 2021-07-15 LK https://hdl.handle.net/20.500.14352/5036 UL https://hdl.handle.net/20.500.14352/5036 LA eng NO Carlos III Institute of Health DS Docta Complutense RD 2 may 2024