TY - JOUR AU - Garcillán Goyoaga, Beatriz de AU - Fuentes, Patricia AU - Marín Marín, Ana Victoria AU - Fernández Megido, Rebeca AU - Chacón Arguedas, Carlos Daniel AU - S. Mazariegos, Marina AU - González Laborda, Raquel AU - Jiménez Reinoso, Anaïs AU - Muñoz Ruiz, Miguel AU - Cárdenas Mastracusa, Paula AU - Fernández-Malavé, Edgar AU - Toribio, Maria Luisa AU - Regueiro González-Barros, José Ramón PY - 2021 DO - 10.3389/fcell.2021.608490 SN - 2296-634X UR - https://hdl.handle.net/20.500.14352/8553 T2 - Frontiers in Cell and Developmental Biology AB - The human αβ T-cell receptor (TCR) is composed of a variable heterodimer (TCRαβ) and three invariant dimers (CD3γε, CD3δε, and ζζ/CD2472). The role of each invariant chain in the stepwise interactions among TCR chains along the assembly is still not... LA - eng PB - Frontiers Media KW - CD3G KW - CD3D KW - shRNA knockdown KW - T-cell receptor (TCR) KW - TCR assembly KW - T-cell progenitors KW - immunodeficiency TI - CD3G or CD3D Knockdown in Mature, but Not Immature, T Lymphocytes Similarly Cripples the Human TCRαβ Complex TY - journal article VL - 9 ER -