RT Journal Article
T1 C-protein reactive as a marker of surgical stress reduction with an ERAS protocol (enhanced recovery after surgery) in colorectal surgery: a proxpective cohort study.
A1 Cabellos. Mercedes, 
A1 Labalde Martínez, María
A1 Torralba, Miguel
A1 Rodríguez Fraile, José Ramón
A1 Atance Martínez, Juan Carlos
AB Background: The aim of this study is to evaluate the effectiveness of an Enhanced Recovery After Surgery Protocol (ERAS) in relation to reduce the Systemic Inflammatory Response (SIR) to surgery using C-reactive protein (CRP) in the first (POD1), second (POD2) and third (POD3) postoperative day.Methods: We enrolled 121 patients (ERAS group) that underwent elective colorectal surgery with ERAS, and compared them with 135 patients (preERAS group) that had undergone surgery prior to the implementation. We made a univariate analysis to compare the CRP values in POD1, POD2, and POD3 between preERAS/ERAS group, laparoscopic/open surgery and the presence or not of Clavien Dindo complications. Multivariable lineal regression was used to assess if the ERAS had a decreasing effect on the CRP in POD1, POD2, and POD3, and was adjusted by age, male sex, use of laparoscopy, and complications.Results: The presence of complications was independently associated with an increase in CRP values ​​in POD1, POD2, and POD3. Laparoscopy in POD1 and POD2, and ERAS in POD2 was independently associated with a decrease in CRP values.Conclusion: The analysis shows an increase in SIR measured as a CRP value in those patients that had complications. The SIR decreased with laparoscopy in POD1 and POD2 and with ERAS in POD2.
PB Wiley
SN 0022-4790
YR 2018
FD 2018-03-15
LK https://hdl.handle.net/20.500.14352/98964
UL https://hdl.handle.net/20.500.14352/98964
LA eng
NO Cabellos Olivares M, Labalde Martínez M, Torralba M, Rodríguez Fraile JR, Atance Martínez JC. C-reactive protein as a marker of the surgical stress reduction within an ERAS protocol (Enhanced Recovery After Surgery) in colorectal surgery: A prospective cohort study. J Surg Oncol. 2018;117:717–724. https://doi.org/10.1002/jso.24909
DS Docta Complutense
RD 23 abr 2025