RT Journal Article T1 PeneloPET v3.0, an improved multiplatform PET Simulator A1 López Montes, Alejandro A1 López Herraiz, Joaquín A1 Galve Lahoz, Pablo A1 España Palomares, Samuel A1 Vicente, Esther A1 Cal Gonzalez, Jacobo A1 Udías Moinelo, José Manuel AB PeneloPET is a Monte Carlo simulation tool for positron emission tomography based on PENELOPE. It was developed by the Nuclear Physics Group at University Complutense of Madrid and its initial version was released in 2009. In this work, we present PeneloPET v3.0, which is now available precompiled for Microsoft Windows, MacOS and Linux OS. This new release includes improved simulations of the positron range in different materials and an accurate description of the decay cascades for many radioactive nuclei including the most common non-pure positron emitters used in PET. This enables the simulation of PET acquisitions with positron-gamma emitters. This release also includes many different fully-working examples, of both clinical and preclinical scanners, as well as several numerical phantoms. Due to the simplicity of the input the output files, and the installation process, PeneloPET v3.0 can be perfectly used not only for research, but also as an educational tool in class. PB IEEE SN 1095-7863 YR 2019 FD 2019 LK https://hdl.handle.net/20.500.14352/12421 UL https://hdl.handle.net/20.500.14352/12421 LA eng NO IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC) (2019. Manchester, England). This is a contribution to the Moncloa Campus of International Excellence. Part of the calculations of this work were performed in the "Cluster de Cálculo para Técnicas Físicas" funded in part by UCM and in part by UE Regional Funds. We acknowledge support from the Spanish Government (FPA2015-65035-P, RTC-2015-37722), from Comunidad de Madrid (S2013/MIT-3024 TOPUS-CM, B2017/BMD-3888 PRONTO-CM) and European Regional Funds. This work is also supported by EU's H2020 under MediNet, a Networking Activity of ENSAR-2 (grant agreement 654002). This work is also supported by NIH R01 CA215700-2 grant. NO Unión Europea. Horizonte 2020 NO Ministerio de Ciencia e Innovación (MICINN) NO Comunidad de Madrid/ FEDER NO NIH National Institutes of Health - USA NO UCM DS Docta Complutense RD 20 abr 2025