RT Journal Article T1 Inferring the Dynamics of "Hidden" Neurons from Electrophysiological Recordings A1 Makarov Slizneva, Valeriy A1 Castellanos, Nazareth P. AB Statistical analysis of electrophysiological recordings obtained under, e.g. tactile, stimulation frequently suggests participation in the network dynamics of experimentally unobserved "hidden" neurons. Such interneurons making synapses to experimentally recorded neurons may strongly alter their dynamical responses to the stimuli. We propose a mathematical method that formalizes this possibility and provides an algorithm for inferring on the presence and dynamics of hidden neurons based on fitting of the experimental data to spike trains generated by the network model. The model makes use of Integrate and Fire neurons "chemically" coupled through exponentially decaying synaptic currents. We test the method on simulated data and also provide an example of its application to the experimental recording from the Dorsal Column Nuclei neurons of the rat under tactile stimulation of a hind limb. PB World Academy of Science, Engineering & Technology SN 1307-6884 YR 2006 FD 2006 LK https://hdl.handle.net/20.500.14352/50155 UL https://hdl.handle.net/20.500.14352/50155 LA eng NO Conference of the World-Academy-of-Science-Engineering-and-Technology. Barcelona, SPAIN. OCT 22-24, 2006. NO Universidad Complutense de Madrid NO Ministerio de Educacion y Ciencia (Ramón y Cajal) DS Docta Complutense RD 13 jul 2025