%0 Journal Article
%A Ríos Dueñas, Esther
%A Medrano, Sara
%A Álvarez, Mar
%A Valderrama Conde, María José
%A Vallejo, Luis
%A Delgado-Iribarren García-Campero, Albert
%A Culebras López, Esther
%T High performance of the automated ADVIA Centaur Systems SARS-CoV-2 Antigen Assay in nasopharyngeal samples with high viral load
%D 2022
%@ 1139-6709
%U https://hdl.handle.net/20.500.14352/123653
%X ADVIA Centaur SARS-CoV-2 Antigen (COV2Ag) Assay (Siemens Healthineers) was evaluated for SARS-CoV-2 detection. A total of 141 nasopharyngeal samples were analyzed by this technique and results were compared with those obtained by quantitative reverse-transcription polymerase chain reaction (RT-PCR). The overall sensitivity and specificity of the test were 68.70% and 70%, respectively. Regarding cycle threshold (Ct) values, the COV2Ag test showed a sensitivity of 93.75% and 100% for nasopharyngeal samples with Ct < 25 and < 20, respectively. ADVIA Centaur COV2Ag Assay is a useful, automated, and rapid technique for early SARS-CoV-2 diagnosis and isolation of the infected individuals, avoiding its transmission.
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