TY  - JOUR
AU  - Acosta, Javier
AU  - Pérez, Elena
AU  - Sánchez Murcia, Pedro A.
AU  - Fillat, Cristina
AU  - Fernández Lucas, Jesús
PY  - 2021
DO  - 10.3390/biom11010120
UR  - https://hdl.handle.net/20.500.14352/109083
T2  - Biomolecules
AB  - Herein we report the first proof for the application of type II 2′-deoxyribosyltransferase from Lactobacillus delbrueckii (LdNDT) in suicide gene therapy for cancer treatment. To this end, we first confirm the hydrolytic ability of LdNDT over the...
LA  - eng
M2  - 1
PB  - MDPI
KW  - Chemotherapy
KW  - Suicide gene therapy
KW  - Nucleoside analogues
KW  - 2′-deoxyribosyltransferase
KW  - Structural bioinformatics
KW  - Molecular dynamics
TI  - Molecular basis of NDT-mediated activation of nucleoside-based prodrugs and application in suicide gene therapy
TY  - journal article
VL  - 11
ER  -