RT Journal Article
T1 Development of the Interosseous Muscles of the Human Hand: Morphological and Functional Aspects of the Terminal Insertion
A1 Maldonado Bautista, Estela
A1 Martínez Sanz, Elena
A1 Catón Vázquez, Francisco Javier
A1 Arráez Aybar, Luis Alfonso
A1 Barrio Asensio, María Del Carmen
A1 Naredo, Esperanza
A1 Murillo González, Jorge Alfonso
A1 Mérida Velasco, José Ramón
AB Introduction: To date, there have been no studies conducted on the development of interosseous muscles (IO) in the human hand. This study aimed to investigate the development of these muscles in order to clarify their terminal insertions and their relationship with the metacarpophalangeal joints.Methods: Serial sections of 25 human specimens (9 embryos and 16 fetuses) between the 7th and 14th week of development, sourced from the Collection of the Department of Anatomy and Embryology at UCM Faculty of Medicine, were analysed bilaterally using a conventional optical microscope.Results: Our findings revealed that, during the 7th week of development, the metacarpophalangeal interzone mesenchyme extended into the extensor apparatus of the fingers. Furthermore, we observed that the joint capsule and the tendon of the IO derive from the articular interzone mesenchyme. By the end of the 7th week, corresponding to Carnegie stage 21, the myotendinous junction appeared, initiating cavitation of the metacarpophalangeal joint. During the fetal period, the terminal insertions of the IO were identified: both the dorsal interosseous (DI) and palmar interosseous (PI) muscles insert into the metacarpophalangeal joint capsule and establish a connection with the volar plate located at the base of the proximal phalanx and the extensor apparatus. Some muscle fibres also attach to the joint capsule at the level of the proximal synovial cul-de-sac. The functional implications of these findings are discussed within this work.Conclusion: This study provides the first detailed description of the development of the interosseous muscles in the human hand.
PB S. Karger AG
SN 1422-6405
YR 2024
FD 2024-08-06
LK https://hdl.handle.net/20.500.14352/107469
UL https://hdl.handle.net/20.500.14352/107469
LA eng
NO Maldonado, E., Martínez-Sanz, E., Catón, J., Arráez-Aybar, L. A., Barrio, M. C., Naredo, E., Murillo-González, J. A., & Mérida-Velasco, J. R. (2024). Development of the Interosseous Muscles of the Human Hand: Morphological and Functional Aspects of the Terminal Insertion. Cells, tissues, organs, 10.1159/000540760. Advance online publication. https://doi.org/10.1159/000540760
NO Banco Santander/Universidad Complutense de Madrid
NO Complutense Research Group
DS Docta Complutense
RD 12 abr 2025