RT Journal Article
T1 Associations of Dietary Intake and Nutrient Status with Micronutrient and Lipid Composition in Breast Milk of Donor Women
A1 Ureta-Velasco, Noelia
A1 Montealegre-Pomar, Adriana
A1 Keller, Kristin
A1 Escuder Vieco, Diana
A1 Fontecha, Javier
A1 Calvo, María V.
A1 Megino-Tello, Javier
A1 Serrano, José C. E.
A1 García-Lara, Nadia Raquel
A1 Pallas Alonso, Carmen Rosa
AB The influence of the diet and nutritional status of milk donors on the nutritional composition of donor human milk (DHM) is unknown. The present study aimed to determine the nutritional profile of DHM and the associations between donors’ dietary intake and nutritional status and the micronutrient and lipid composition in DHM. For this purpose, 113 donors completed a food frequency questionnaire, provided a five-day weighed dietary record, and collected milk for five consecutive days. Nutrient determinations in donors’ erythrocytes, plasma, urine, and milk were performed. Multiple linear regressions were conducted for the evaluation of the associations. We highlight the following results: DHM docosahexaenoic acid (DHA) was positively associated with donors’ plasma DHA content and donors’ DHA intake (R2 0.45, p < 0.001). For every 1 g/day DHA intake, an increase of 0.38% in DHA content and 0.78% in total omega-3 content was observed in DHM (R2 0.29, p < 0.001). DHM saturated fatty acids were positively associated with erythrocyte dimethyl acetals, plasma stearic acid, trans fatty acids intake, and breastfeeding duration and negatively associated with erythrocyte margaroleic acid (R2 0.34, p < 0.01). DHM cholecalciferol was associated with plasma cholecalciferol levels and dairy intake (R2 0.57, p < 0.01). Other weaker associations were found for free thiamin, free riboflavin, pyridoxal, dehydroascorbic acid, and the lipid profile in DHM. In conclusion, the diet and nutritional status of donors influence the fatty acid profile and micronutrient content of DHM.
PB MPDI
SN 2072-6643
YR 2023
FD 2023-08-07
LK https://hdl.handle.net/20.500.14352/103597
UL https://hdl.handle.net/20.500.14352/103597
LA eng
NO Ureta-Velasco, N., Montealegre-Pomar, A., Keller, K., Escuder-Vieco, D., Fontecha, J., Calvo, M. V., Megino-Tello, J., Serrano, J. C. E., García-Lara, N. R., & Pallás-Alonso, C. R. (2023). Associations of Dietary Intake and Nutrient Status with Micronutrient and Lipid Composition in Breast Milk of Donor Women. Nutrients, 15(15), 3486. https://doi.org/10.3390/nu15153486
NO Instituto de Salud Carlos III (España)
NO Ministerio de Ciencia, Innovación y Universidades (España)
DS Docta Complutense
RD 17 abr 2025