RT Journal Article
T1 Changes in Biceps femoris Transcriptome along Growth in Iberian Pigs Fed Different Energy Sources and Comparative Analysis with Duroc Breed
A1 Benítez, Rita
A1 Núñez, Yolanda
A1 Ayuso, Miriam
A1 Isabel Redondo, Beatriz
A1 Fernández Barroso, Miguel A.
A1 De Mercado, Eduardo
A1 Gómez Izquierdo, Emilio
A1 García Casco, Juan M.
A1 López Bote, Clemente José
A1 Óvilo, Cristina
AB This experiment was conducted to investigate the effects of developmental stage, breed, and diet energy source on the genome-wide expression, meat quality traits, and tissue composition of biceps femoris muscle in growing pure Iberian and Duroc pigs. The study comprised 59 Iberian (IB) and 19 Duroc (DU) animals, who started the treatment at an average live weight (LW) of 19.9 kg. The animals were kept under identical management conditions and fed two diets with different energy sources (6% high oleic sunflower oil or carbohydrates). Twenty-nine IB animals were slaughtered after seven days of treatment at an average LW of 24.1 kg, and 30 IB animals plus all the DU animals were slaughtered after 47 days at an average LW of 50.7 kg. The main factors affecting the muscle transcriptome were age, with 1832 differentially expressed genes (DEGs), and breed (1055 DEGs), while the effect of diet on the transcriptome was very small. The results indicated transcriptome changes along time in Iberian animals, being especially related to growth and tissue development, extracellular matrix (ECM) composition, and cytoskeleton organization, with DEGs affecting relevant functions and biological pathways, such as myogenesis. The breed also affected functions related to muscle development and cytoskeleton organization, as well as functions related to solute transport and lipid and carbohydrate metabolism. Taking into account the results of the two main comparisons (age and breed effects), we can postulate that the Iberian breed is more precocious than the Duroc breed, regarding myogenesis and muscle development, in the studied growing stage.
PB MPDI
SN 2076-2615
YR 2021
FD 2021-12-08
LK https://hdl.handle.net/20.500.14352/5021
UL https://hdl.handle.net/20.500.14352/5021
LA eng
NO Comunidad de Madrid/FEDER
NO Ministerio de Economía y Competitividad
DS Docta Complutense
RD 18 abr 2025